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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Neurobiol Dis. 2014 May 27;69:192–199. doi: 10.1016/j.nbd.2014.05.024

Fig. 2. Effects of Treatment on Organ Weight at 96h and 5 weeks post HI and Lung Bleeding.

Fig. 2

The absolute spleen weight in the vehicle group was significantly lower than the sham group at 5 weeks post HI. There was no intergroup difference in the spleen to body weight ratio at 96h or 5 weeks (A). There was a significant increase in the lung to body weight ratio in vehicle group at 5 weeks post HI when compared to sham (B). Treatment groups improved lung to body weight ratio (p>0.05 vs. Sham). The graph in part (C) shows the severity of lung bleeding at 5 weeks post HI. It is graded on a scale from 0 to 3, with zero meaning no bleeding at all and 3 meaning more than ¾ of lung bleeding. The vehicle group showed severe bleeding compared to sham; while G-CSF significantly reduced lung bleeding compared to vehicle, G-CSF+Ab treatment group also showed tendency to reduce bleeding but significance was not reached (Data represent +/− SEM; *p<0.05 vs. sham, #p<0.05 vs. vehicle).