Table 2.
Changes in hemodynamic indices, body weight, and function capacity.
| Item | At baseline | 4 weeks later | 8 weeks later | 12 weeks later |
|---|---|---|---|---|
| Systolic blood pressure (mmHg) | ||||
| Testosterone group | 119.92 ± 16.99 | 121.60 ± 12.99 | 122.84 ± 9.49 | 125.92 ± 15.67 |
| Placebo group | 126.12 ± 18.87 | 122.24 ± 19.17 | 121.24 ± 18.38 | 120.74 ± 28.45 |
| P value | 0.232 | 0.891 | 0.700 | 0.434 |
| Diastolic blood pressure (mmHg) | ||||
| Testosterone group | 81.17 ± 18.77 | 75.80 ± 9.70 | 76.44 ± 7.58 | 79.00 ± 9.99 |
| Placebo group | 79.04 ± 8.94 | 73.76 ± 8.95 | 72.68 ± 19.27 | 76.13 ± 8.26 |
| P value | 0.613 | 0.444 | 0.369 | 0.286 |
| Heart rate (bpm∗) | ||||
| Testosterone group | 71.21 ± 8.83 | 70.48 ± 9.49 | 69.92 ± 6.84 | 70.88 ± 8.78 |
| Placebo group | 69.52 ± 7.56 | 71.28 ± 7.12 | 68.56 ± 8.60 | 71.52 ± 7.94 |
| P value | 0.738 | 0.539 | 0.792 | |
| Body weight (Kg) | ||||
| Testosterone group | 76.66 ± 10.42 | 75.88 ± 10.35 | 75.84 ± 10.26 | 75.46 ± 9.96 |
| Placebo group | 73.12 ± 12.67 | 74.00 ± 12.47 | 74.28 ± 11.92 | 74.52 ± 11.92 |
| P value | 0.286 | 0.565 | 0.622 | 0.768 |
| 6MWD† (m) | ||||
| Testosterone group | 407.44 ± 100.23 | 466.58 ± 93.33 | 476.67 ± 96.59 | 491.65 ± 112.88 |
| Placebo group | 338.25 ± 125.60 | 394.17 ± 98.37 | 421.52 ± 99.14 | 416.09 ± 121.57 |
| P value | 0.038 | 0.012 | 0.044 | 0.034 |
| Muscle strength (kgf) | ||||
| Testosterone group | 37.64 ± 9.64 | 39.60 ± 8.19 | 41.60 ± 9.57 | 42.12 ± 9.06 |
| Placebo group | 35.17 ± 10.54 | 36.68 ± 6.87 | 38.88 ± 7.73 | 38.65 ± 8.17 |
| P value | 0.411 | 0.178 | 0.278 | 0.170 |
*Beats per minute.
†Six-minute walk distance.
Data are presented as mean ± SD.