Fig. 4.

The NMDAR activity of spinal lamina II neurons does not change in RTX-induced painful neuropathy and diabetic neuropathic pain. (A) Representative traces show evoked NMDAR-EPSCs and AMPAR-EPSCs of a lamina II neuron from one vehicle-treated, one RTX-treated, and one diabetic rat. (B) Summary data show the amplitude of evoked NMDAR-EPSCs and AMPAR-EPSCs (left) and the ratio of NMDAR-EPSCs to AMPAR-EPSCs in lamina II neurons of vehicle-treated (n = 10 neurons), RTX-treated (n = 9 neurons), and diabetic (n = 10 neurons) rats. Error bars represent the S.E.M.