Fig. 7.

CK2 plays a critical role in nerve injury–induced increase in the postsynaptic NMDAR activity of spinal dorsal horn neurons. (A and B) Original traces (A) and mean changes (B) in the NMDAR currents elicited by puff NMDA to lamina II neurons in SNL rat spinal slices treated with vehicle (dimethylsulfoxide, n = 19 neurons) or DRB (n = 23 neurons). (C) Summary data show AMPAR- and NMDAR-mediated mEPSCs of lamina II neurons in spinal cord slices treated with vehicle or DRB in sham control and SNL rats. *P < 0.05 compared with the vehicle control group. Error bars represent the S.E.M.