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. 2014 Aug;350(2):425–434. doi: 10.1124/jpet.114.213470

TABLE 3.

Gestational age–dependent maternal-fetal AUCs of glyburide using noncompartmental analyses

Data are reported as the mean (95% confidence interval).

Parameter gd 15
gd 19
Mean Mean P Value
Maternal AUC0–240 min (ng⋅min⋅ml−1) 26,129 (20,129–32,478) 24,216 (19,576–30,273) 0.657
Fetal AUC0–240 min (ng⋅min⋅g−1) 462 (349–529) 905 (726–1013)a <0.001a
Fetal/maternal AUC ratio (%) 1.8 (1.4–2.2) 3.7 (2.8–4.6)a 0.007a
a

Statistically significant (P < 0.05) differences between gd 19 and 15.