Figure 5. Increased DNA damage and apoptosis of lymphoid cells following loss of Recql4.

(A) Intracellular cleaved caspase-3 and γH2AX costaining B cell fractions of the BM. (B) Quantitation of cleaved caspase-3 and γH2AX in B cells as either the percentage or absolute number of positive cells per femur. (C) Total BM and thymus cleaved caspase-3 and γH2AX. Data expressed as mean ± SEM, Student’s t test. *P < 0.05. n ≥ 3 per genotype.