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. 2014 Jul 8;124(8):3612–3616. doi: 10.1172/JCI75214

Figure 2. Intraspinal transplantation of GABAergic precursor (MGE) cells reduces excessive scratching, biting, and licking in Bhlhb5 mutant mice.

Figure 2

Bhlhb5 mutant mice exhibit excessive licking, biting, and scratching (baseline). This spontaneous behavior usually developed around 4 weeks of age. Two weeks after transplantation, these behaviors were significantly reduced in mice that received MGE cells (red, n = 6; –70%, *P < 0.05). In contrast, these behaviors persisted in control animals (black, n = 7; –12% NS). Scratching behavior was measured in minutes over a 30-minute period of observation. The illustration to the right displays the individual data points.