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MYC-regulated microRNAs and their cell-cycle-related targets. The MYC-stimulated cyclin D1/2/3 (green), cyclin E1/2 (orange), and CDK-4/-6 (purple), and the MYC-repressed p21 (red) are shown. E2F (pink) is both MYC-stimulated and -repressed. Each stage of the cell cycle regulated by these targets is represented and the coordinated regulation of these targets promotes cell-cycle progression.
