Table 5.
Accuracy Measures Stratified by Age, Sex, and Race in Any Stroke Cohort
| Algorithm | Category | No. | PPV (95% CI), % | Sensitivity (95% CI), % | Specificity (95% CI), % | NPV (95% CI), % |
|---|---|---|---|---|---|---|
| AIS | Age | |||||
| 65 y | 1915 | 85.4 (70.6-100) | 44.2 (29.3-59.1) | 99.8 (99.6-100) | 98.7 (98.2-99.2) | |
| 65-74 y | 9713 | 90.7 (85.3-96.0) | 56.0 (48.8-63.2) | 99.9 (99.8-100) | 99.2 (99.0-99.3) | |
| ≥ 75 y | 3461 | 87.8 (81.6-93.9) | 66.4 (58.7-74.1) | 99.6 (99.4-99.8) | 98.6 (98.2-99.0) | |
| Sex | ||||||
| Female | 7804 | 92.0 (87.1-96.9) | 62.6 (55.4-69.8) | 99.9 (99.8-100) | 99.2 (98.9-99.4) | |
| Male | 7285 | 85.8 (87.1-96.9) | 55.2 (48.3-62.2) | 99.7 (99.6-99.9) | 98.8 (98.5-99.0) | |
| Race | ||||||
| Black | 5574 | 93.0 (88.3-97.6) | 66.1 (58.8-73.3) | 99.8 (99.7-100) | 99.0 (98.7-99.2) | |
| White | 9515 | 86.5 (80.6-92.5) | 53.3 (46.5-60.1) | 99.8 (99.7-99.9) | 99.0 (98.8-99.2) | |
| ICH | Age | |||||
| < 65 y | 1915 | — | — | — | — | |
| 65-74 y | 9713 | 85.4 (71.3-99.5) | 67.3 (50.7-84.0) | 100.0 (99.9-100) | 99.9 (99.8-100) | |
| ≥ 75 y | 3461 | 93.8 (81.0-100) | 69.4 (49.9-88.8) | 100.0 (99.9-100) | 99.8 (99.7-100) | |
| Sex | ||||||
| Female | 7804 | 86.7 (71.0-100) | 77.8 (59.6-96.0) | 100.0 (99.9-100) | 99.9 (99.9-100) | |
| Male | 7285 | 91.3 (79.8-100) | 61.6 (45.3-78.0) | 100.0 (99.9-100) | 99.8 (99.7-99.9) | |
| Race | ||||||
| Black | 5574 | 81.4 (64.4-98.5) | 82.5 (65.7-99.2) | 99.9 (99.9-100) | 99.9 (99.9-100) | |
| White | 9515 | 95.2 (86.1-100) | 59.1 (42.5-75.6) | 100.0 (100-100) | 99.9 (99.8-99.9) | |
| AIS/ICH | Age | |||||
| < 65 y | 1915 | 86.1 (71.9-100) | 45.5 (30.7-60.3) | 99.8 (99.6-100) | 98.7 (98.2-99.2) | |
| 65-74 y | 9713 | 92.2 (87.7-96.8) | 57.9 (51.3-64.5) | 99.9 (99.8-100) | 99.1 (98.9-99.2) | |
| ≥ 75 y | 3461 | 90.1 (84.9-95.4) | 67.9 (60.7-75.0) | 99.6 (99.4-99.8) | 98.4 (98.0-98.8) | |
| Sex | ||||||
| Female | 7804 | 93.1 (88.8-97.4) | 64.2 (57.5-71.0) | 99.9 (99.8-100) | 99.1 (98.9-99.3) | |
| Male | 7285 | 88.3 (83.1-93.5) | 57.3 (50.9-63.7) | 99.8 (99.6-99.9) | 98.6 (98.4-98.9) | |
| Race | ||||||
| Black | 5574 | 93.1 (88.9-97.4) | 68.8 (62.1-75.5) | 99.8 (99.7-99.9) | 99.0 (98.7-99.2) | |
| White | 9515 | 89.3 (84.3-94.3) | 54.6 (48.3-60.9) | 99.8 (99.7-99.9) | 98.8 (98.6-99.1) |
Abbreviations: AIS, acute ischemic stroke; ICH, intracranial hemorrhage; NPV, negative predictive value; PPV, positive predictive value.