Table 3.
Marker | Genotype | χ 2, P value | Allele | P value | OR (95% CI) | Power | |||
---|---|---|---|---|---|---|---|---|---|
rs45576939 | A/A | A/G | G/G | A | G | 0.173 | 0.235 (0.029, 1.889) | 28% | |
Patients | 0 (0) | 1 (0.01) | 97 (0.99) | χ 2 = 2.231 | 1 (0.01) | 195 (0.99) | |||
Controls | 0 (0) | 8 (0.043) | 179 (0.957) | P = 0.135 | 8 (0.021) | 366 (0.979) | |||
rs3729842 | C/C | C/T | T/T | C | T | 0.865 | 1.042 (0.651, 1.667) | 5.4% | |
Patients | 74 (0.755) | 16 (0.163) | 8 (0.082) | χ 2 = 4.282 | 164 (0.837) | 32 (0.163) | |||
Controls | 135 (0.722) | 45 (0.241) | 7 (0.037) | P = 0.118 | 315 (0.842) | 59 (0.158) | |||
rs3729843 | A/A | A/G | G/G | A | G | 0.002 | 1.889 (1.252, 2.852) | 85.2% | |
Patients | 11 (0.112) | 33 (0.337) | 54 (0.551) | χ 2 = 8.315 | 55 (0.281) | 141 (0.719) | |||
Controls | 7 (0.037) | 50 (0.267) | 130 (0.695) | P = 0.004 | 64 (0.171) | 310 (0.829) | |||
rs1892028 | A/A | A/G | G/G | A | G | 0.140 | 0.770 (0.544, 1.090) | 31.3% | |
Patients | 31 (0.313) | 54 (0.5) | 14 (0.143) | χ 2 = 4.719 | 116 (0.586) | 82 (0.414) | |||
Controls | 55 (0.294) | 86 (0.460) | 47 (0.251) | P = 0.094 | 196 (0.521) | 180 (0.479) | |||
rs10800775 | C/C | C/T | T/T | C | T | 0.152 | 0.766 (0.533, 1.103) | 29.7% | |
Patients | 46 (0.465) | 45 (0.455) | 9 (0.090) | χ 2 = 2.142 | 137 (0.685) | 63 (0.315) | |||
Controls | 73 (0.388) | 89 (0.473) | 26 (0.138) | P = 0.343 | 235 (0.625) | 141 (0.375) | |||
rs7544061 | T/T | T/C | C/C | T | C | 0.612 | 0.821 (0.383, 1.761) | 73% | |
Patients | 0 (0) | 10 (0.101) | 89 (0.899) | χ 2 = 0.274 | 10 (0.051) | 188 (0.949) | |||
Controls | 0 (0) | 23 (0.116) | 166 (0.834) | P = 0.601 | 23 (0.061) | 355 (0.939) | |||
rs3767545 | A/A | A/G | G/G | A | G | 0.294 | 1.680 (0.638, 4.424) | 20.3% | |
Patients | 0 (0) | 8 (0.081) | 91 (0.919) | χ 2 = 1.160 | 8 (0.04) | 190 (0.960) | |||
Controls | 0 (0) | 9 (0.049) | 175 (0.951) | P = 0.282 | 9 (0.024) | 359 (0.976) | |||
rs3729547 | C/C | T/C | T/T | C | T | 0.033 | 0.679 (0.475, 0.970) | 56.9% | |
Patients | 9 (0.092) | 51 (0.520) | 38 (0.388) | χ 2 = 5.679 | 69 (0.352) | 127 (0.648) | |||
Controls | 37 (0.196) | 94 (0.497) | 58 (0.307) | P = 0.058 | 168 (0.444) | 210 (0.556) | |||
rs3767546 | A/A | A/T | T/T | A | T | 0.457 | 0.751 (0.353, 1.597) | 10.6% | |
Patients | 0 (0) | 10 (0.102) | 89 (0.908) | χ 2 = 0.816 | 10 (0.051) | 188 (0.949) | |||
Controls | 1 (0.005) | 23 (0.122) | 165 (0.873) | P = 0.665 | 25 (0.067) | 353 (0.934) | |||
rs117962659 | C/C | C/A | A/A | C | A | 0.186 | 1.920 (0.730, 5.049) | 12.4% | |
Patients | 0 (0) | 6 (0.061) | 93 (0.939) | χ 2 = 0.895 | 6 (0.030) | 192 (0.970) | |||
Controls | 1 (0.005) | 15 (0.080) | 172 (0.915) | P = 0.639 | 17 (0.045) | 359 (0.955) | |||
rs2275860 | A/A | A/G | G/G | A | G | 0.448 | 0.745 (0.351, 1.588) | 10.8% | |
Patients | 1 (0.010) | 8 (0.081) | 90 (0.909) | χ 2 = 3.564 | 10 (0.051) | 188 (0.949) | |||
Controls | 0 (0) | 25 (0.133) | 163 (0.867) | P = 0.168 | 25 (0.066) | 351 (0.934) | |||
c.192 + 353 C/A | C/C | C/A | A/A | C | A | 0.022 | 0.095 (0.013, 0.714) | 87.2% | |
Patients | 98 (0.990) | 1 (0.010) | 0 (0) | χ 2 = 8.333 | 197 (0.995) | 1 (0.005) | |||
Controls | 168 (0.898) | 19 (0.102) | 0 (0) | P = 0.004 | 355 (0.949) | 19 (0.051) | |||
c.192 + 463 G/A | G/G | A/G | A/A | G | A | 0.019 | 0.090 (0.012, 0.675) | 89.7% | |
Patients | 98 (0.99) | 1 (0.01) | 0 (0) | χ 2 = 8.925 | 197 (0.995) | 1 (0.005) | |||
Controls | 167 (0.893) | 20 (0.107) | 0 (0) | P = 0.003 | 354 (0.947) | 20 (0.053) |
Note: OR: odds ratio, at which the minor allele was viewed as an exposure factor in this case-control study.