Table 2.
Baseline Characteristics of Women Receiving Nevirapine- and Lopinavir/ritonavir-Based Antiretroviral Therapy
| NVP-based ART (n=370) | LPV/RTV-based ART (n=371) | Total (n=741) | ||
|---|---|---|---|---|
| Age at randomization (years) | Mean±SD (No.) | 33.5±7.0 (370) | 33.4±7.2 (371) | 33.5±7.1 (741) |
| CD4 count (cells/mm3) | Mean±SD (No.) | 130±66 (370) | 128±68 (371) | 129±67 (741) |
| HIV-1 RNA (log10 copies/mL) | Mean±SD (No.) | 5.1±0.6 (370) | 5.1±0.6 (371) | 5.1±0.6 (741) |
| Total cholesterol (mg/dL) | Mean±SD (No.) | 133±32 (361) | 130±31 (368) | 132±32 (729) |
| <200 (mg/dL), No. (%) | 353 (98) | 357 (97) | 710 (97) | |
| HDL (mg/dL) | Mean±SD (No.) | 34±15 (356) | 34±13 (363) | 34±14 (719) |
| >=40 (mg/dL), No. (%) | 104 (29) | 107 (29) | 211 (29) | |
| Non-HDL (mg/dL) | Mean±SD (No.) | 99±28 (356) | 96±28 (363) | 98±28 (719) |
| <160 (mg/dL), No. (%) | 364 (98) | 361 (97) | 725 (98) | |
| LDL (mg/dL) | Mean±SD (No.) | 81±27 (356) | 80±27 (366) | 81±27 (722) |
| <130 (mg/dL), No. (%) | 346 (97) | 352 (96) | 698 (97) | |
| Triglycerides (mg/dL) | Mean±SD (No.) | 103±61 (361) | 97±51 (367) | 100±56 (728) |
| <150 (mg/dL), No. (%) | 311 (86) | 323 (88) | 634 (87) | |
| Blood pressure-systolic (mmHg) | Mean±SD (No.) | 112±16 (370) | 112±15 (371) | 112±16 (741) |
| <140 (mmHg), No. (%) | 346 (94) | 358 (96) | 704 (95) | |
| Blood pressure-diastolic (mmHg) | Mean±SD (No.) | 73±12 (370) | 73±11 (371) | 73±11 (741) |
| <90 (mmHg), No. (%) | 337 (91) | 346 (93) | 683 (92) | |
| Blood pressure (mmHg) | <140/90 (mmHg), No. (%) | 331 (89) | 342 (92) | 673 (91) |
| Body mass index (kg/m2) | Mean±SD (No.) | 23.7±4.9 (370) | 23.5±4.7 (371) | 23.6±4.8 (741) |
| <16.5 (kg/m2), No. (%) | 6 (2) | 6 (2) | 12 (2) | |
| >=16.5, <25 (kg/m2), No. (%) | 257 (69) | 251 (68) | 508 (69) | |
| >=25, <30 (kg/m2), No. (%) | 63 (17) | 78 (21) | 141 (19) | |
| >30 (kg/m2), No. (%) | 44 (12) | 36 (10) | 80 (11) | |
| Glucose (mg/dL) | Mean±SD (No.) | 82±21 (357) | 84±18 (366) | 83±20 (723) |
| <110 (mg/dL), No. (%) | 335 (94) | 338 (92) | 673 (93) |
1
Abbreviations: NVP, Nevirapine; LPV/RTV, Lopinavir/ritonavir; ART, antiretroviral therapy; SD, standard deviation; HDL, high-density lipoprotein; LDL, low-density lipoprotein.