TABLE 4.
L(I,J) | Treatment Group | |
Oil | VARA | |
Value (day−1) | ||
L(17,26) | 4.26 | 13.9 |
L(0,17) | 0.02 | 0.00 |
L(1,17) | 0.55 | 0.00 |
L(60,17) | 19.4 | 116 |
L(12,10) | 100 | 223 |
L(1,12) | 33.5 | 0.053 |
L(13,10) | 10.0 | 27.0 |
L(1,13) | 4.16 | 0.70 |
L(25,10) | 3.38 | 1.41 |
L(1,25) | 3.92 | 0.04 |
L(15,10) | 89.9 | 439 |
L(1,15) | 14.1 | 5.81 |
L(17,10) | 0.00 | 327 |
L(2,1) | 35.8 | 45.2 |
L(1,2) | 1.46 | 1.18 |
L(0,2) | 0.034 | 0.04 |
L(3,1) | 0.22 | 0.14 |
L(1,3) | 0.33 | 0.12 |
L(4,1) | 3.40 | 3.10 |
L(1,4) | 2.55 | 3.84 |
L(1,4), after dosing day 8 | 9.67 | 7.40 |
L(5,1) | 5.97 | 7.25 |
L(1,5) | 0.52 | 0.57 |
L(0,5) | 0.18 | 0.66 |
L(6,1) | 1.48 | 2.71 |
L(1,6) | 5.00 | 7.37 |
L(1,6), after dosing day 8 | 7.47 | 6.46 |
L(7,1) | 2.81 | 9.75 |
L(1,7) | 0.65 | 1.07 |
L(1,7), after dosing day 8 | 2.39 | 2.07 |
IC(26) | 0.30 | 0.35 |
The data are fractional transfer coefficients [L(I,J)s] or fraction of retinol in compartment J that is transferred to compartment I each day predicted by the integrated model (model 2). The model is shown in Fig. 5.