. Author manuscript; available in PMC: 2014 Jul 24.

Published in final edited form as: Semin Reprod Med. 2014 Feb 10;32(2):141–152. doi: 10.1055/s-0033-1363556

Table 3.

RCTs assessing culture media metabolomics for embryo selection

Study	Outcome measure	Study population (number of embryos)	Day of transfer	Technology	Result
Hardarson et al (2012)^²²	Pregnancy rate	327	2 and 5	NIR	No significant improvement of pregnancy rates.
Vergouw et al (2012)^²³	Live birth rate	417	3	NIR	No significant improvement of live birth rates.
Sfontouris et al (2011)^⁶⁷	Implantation rate	125	2, 3, and 5	NIR	Increased implantation rates following embryo selection based on noninvasive metabolomic analysis.

Abbreviations: NIR, near infrared; RCT, randomized controlled trials.