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. Author manuscript; available in PMC: 2014 Jul 24.
Published in final edited form as: JAMA. 2014 Jan 1;311(1):33–44. doi: 10.1001/jama.2013.282834
ADCS-ADL Inventory Vitamin E (n = 140) Memantine (n = 142) Vitamin E + Memantine (n = 139) Placebo (n = 140)
Baseline score, mean (SD) 57.20 (14.38) 57.77 (13.78) 57.16 (13.59) 56.93 (13.61)
Least squares mean (SE) change from baseline −13.81 (1.11) −14.98 (1.10) −15.20 (1.11) −16.96 (1.11)
Mean change difference compared with placebo (95% CI) 3.15 (0.92 to 5.39) 1.98 (−0.24 to 4.20) 1.76 (−0.48 to 4.00)