Table 4. Predictive values of IC50 in mM (FFAs) for vanadium compounds and in vivo observations IC50 in mM (FFAs) and decreasing blood glucose level.
Compounds | VOSO4 | Complex I | Complex II | Complex III | Complex IV | Complex V |
IC50 predicted | – | 0.50 | 0.75 | 0.53 | 0.93 | 0.87 |
IC50 exp (±S.D.) | 1.0±0.09 | 0.72±0.09 | 0.95±0.09 | 0.54±0.07 | 0.95±0.10 | 0.81±0.06 |
decreasing blood glucose level | 16% | 50% | 33% | 42% | 11% | 26% |