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. 2014 Jul 24;9(7):e102594. doi: 10.1371/journal.pone.0102594

Table 4. Summary of the scoring systems.

Group N (%) Estimated 3-year OS [%] (95% CI) HR (95% CI) P-value
Four-level scores
ABE4
Low (0) 51 (13.5) 94 (88, 100)
Low-intermediate (I) 125 (33.0) 77 (70, 85) 4.15 (1.26, 13.66) 0.0191
High-intermediate (II) 149 (39.3) 63 (55, 71) 7.75 (2.42, 24.78) 0.0006
High (III) 54 (14.2) 35 (24, 52) 18.86 (5.78, 61.58) <0.0001
IPI
Low 90 (24.1) 83 (76, 91)
Low-intermediate 93 (24.9) 75 (66, 84) 1.58 (0.83, 3.03) 0.1663
High-intermediate 98 (26.2) 65 (56, 75) 2.37 (1.29, 4.36) 0.0053
High 93 (24.9) 51 (41, 62) 3.86 (2.14, 6.93) <0.0001
Age-adjusted IPI
Low 83 (22.3) 82 (74, 91)
Low-intermediate 117 (31.5) 77 (70, 85) 1.29 (0.68, 2.43) 0.4357
High-intermediate 106 (28.5) 64 (56, 74) 2.19 (1.20, 3.99) 0.0106
High 66 (17.7) 40 (29, 54) 4.80 (2.64, 8.73) <0.0001
Elderly IPI
Low 142 (38.2) 82 (76, 89)
Low-intermediate 80 (21.5) 72 (63, 83) 1.78 (1.01, 3.16) 0.0484
High-intermediate 91 (24.4) 59 (50, 70) 2.64 (1.59, 4.40) 0.0002
High 59 (15.9) 41 (30, 56) 5.23 (3.10, 8.81) <0.0001
Three-level scores
ABE3
Low 87 (23.0) 92 (86, 98)
Intermediate 231 (61.0) 67 (61, 74) 4.75 (2.19, 10.30) <0.0001
High 61 (16.0) 36 (26, 51) 13.33 (5.93, 29.95) <0.0001
RIPI
Very good 5 (1.3) 80 (51, 100)
Good 178 (47.6) 79 (73, 85) 1.01 (0.14, 7.35) 0.9930
Poor 191 (51.1) 58 (51, 65) 2.37 (0.33, 17.06) 0.3900
ALC/RIPI
Low 164 (43.9) 80 (74, 87)
Intermediate 141 (37.7) 63 (56, 72) 2.12 (1.36, 3.30) 0.0009
High 69 (18.4) 50 (39, 64) 3.14 (1.93, 5.12) <0.0001

Distribution and outcome of patients according to the compared risk scoring systems. Results of the univariate 3-year overall survival analysis: estimated 3-year overall survival (OS) with its 95% confidence interval (CI), hazard rate (HR) with its 95% CI and P-value based on the Cox regression model. Reference group in all regression models is the lowest risk group.

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