Table 4. Summary of the scoring systems.
Group | N (%) | Estimated 3-year OS [%] (95% CI) | HR (95% CI) | P-value | |
Four-level scores | |||||
ABE4 | |||||
Low (0) | 51 (13.5) | 94 (88, 100) | |||
Low-intermediate (I) | 125 (33.0) | 77 (70, 85) | 4.15 (1.26, 13.66) | 0.0191 | |
High-intermediate (II) | 149 (39.3) | 63 (55, 71) | 7.75 (2.42, 24.78) | 0.0006 | |
High (III) | 54 (14.2) | 35 (24, 52) | 18.86 (5.78, 61.58) | <0.0001 | |
IPI | |||||
Low | 90 (24.1) | 83 (76, 91) | |||
Low-intermediate | 93 (24.9) | 75 (66, 84) | 1.58 (0.83, 3.03) | 0.1663 | |
High-intermediate | 98 (26.2) | 65 (56, 75) | 2.37 (1.29, 4.36) | 0.0053 | |
High | 93 (24.9) | 51 (41, 62) | 3.86 (2.14, 6.93) | <0.0001 | |
Age-adjusted IPI | |||||
Low | 83 (22.3) | 82 (74, 91) | |||
Low-intermediate | 117 (31.5) | 77 (70, 85) | 1.29 (0.68, 2.43) | 0.4357 | |
High-intermediate | 106 (28.5) | 64 (56, 74) | 2.19 (1.20, 3.99) | 0.0106 | |
High | 66 (17.7) | 40 (29, 54) | 4.80 (2.64, 8.73) | <0.0001 | |
Elderly IPI | |||||
Low | 142 (38.2) | 82 (76, 89) | |||
Low-intermediate | 80 (21.5) | 72 (63, 83) | 1.78 (1.01, 3.16) | 0.0484 | |
High-intermediate | 91 (24.4) | 59 (50, 70) | 2.64 (1.59, 4.40) | 0.0002 | |
High | 59 (15.9) | 41 (30, 56) | 5.23 (3.10, 8.81) | <0.0001 | |
Three-level scores | |||||
ABE3 | |||||
Low | 87 (23.0) | 92 (86, 98) | |||
Intermediate | 231 (61.0) | 67 (61, 74) | 4.75 (2.19, 10.30) | <0.0001 | |
High | 61 (16.0) | 36 (26, 51) | 13.33 (5.93, 29.95) | <0.0001 | |
RIPI | |||||
Very good | 5 (1.3) | 80 (51, 100) | |||
Good | 178 (47.6) | 79 (73, 85) | 1.01 (0.14, 7.35) | 0.9930 | |
Poor | 191 (51.1) | 58 (51, 65) | 2.37 (0.33, 17.06) | 0.3900 | |
ALC/RIPI | |||||
Low | 164 (43.9) | 80 (74, 87) | |||
Intermediate | 141 (37.7) | 63 (56, 72) | 2.12 (1.36, 3.30) | 0.0009 | |
High | 69 (18.4) | 50 (39, 64) | 3.14 (1.93, 5.12) | <0.0001 |
Distribution and outcome of patients according to the compared risk scoring systems. Results of the univariate 3-year overall survival analysis: estimated 3-year overall survival (OS) with its 95% confidence interval (CI), hazard rate (HR) with its 95% CI and P-value based on the Cox regression model. Reference group in all regression models is the lowest risk group.