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. 2014 Jul 24;9(7):e102989. doi: 10.1371/journal.pone.0102989

Table 2. Comparison of time from identification of patients suspected for MDR-TB to initiation of MDR-TB treatment between pre- and post-LPA period - New Delhi, India.

Steps between identification of patients suspected for MDR-TB and treatment initiation Median time, days (IQR) P-value*
Pre-LPAa Post-LPAb
Step 1: Time from identification of patients suspected for MDR-TB to submission of samplesin the laboratory 12(7–29) 9(4–31) 0.07
Step 2: Time taken in the laboratory to test and provide the MDR-TB report 107(79–131) 5(3–6) <0.0001
Step 3: Time taken from laboratory report to patient reporting to Drug Resistant TB centre 12(4–26) 7(5–13) 0.3
Step 4: Time taken by Drug Resistant TB centre to initiate treatment 8(7–13) 12(9–17) 0.006
TOTAL (Step 1–Step 4) 157(127–200) 38(30–79) <0.001

*P-value generated using the Wilcoxon rank sum test; IQR = Inter-quartile range; MDR-TB = Multidrug resistant Tuberculosis;

a

Solid/liquid culture & Drug Sensitivity Testing (DST).

b

LPA: Line Probe Assay.