Skip to main content
. Author manuscript; available in PMC: 2014 Jul 24.
Published in final edited form as: J Biol Chem. 2006 Mar 23;281(21):15013–15020. doi: 10.1074/jbc.M511116200

FIGURE 1. Hepatic lipid accumulation in the Alb-VP-hPXR transgenic mice expressing the activated PXR.

FIGURE 1

A and B, liver paraffin sections of the wild type (A) and transgenic (B) mice were stained with hematoxylin and eosin. C and D, liver frozen sections of the wild type (C) and transgenic (D) mice were stained with Oil-Red O. CV, central vein. Magnification for all histology panels is ×200. E and F, enlarged liver (E) but not kidney (F) in the transgenic mice. G, the liver and kidney weights measured as percentages of the total body weight. H, growth retardation in the transgenic mice. Male transgenic (TG) mice and their wild type littermates were weaned and weighed at day 22 after birth and weighed every 3 days thereafter. The results are presented as the averages and S.D.