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. Author manuscript; available in PMC: 2015 Jul 15.
Published in final edited form as: Dev Biol. 2014 Apr 26;391(2):230–240. doi: 10.1016/j.ydbio.2014.04.005

Figure 1.

Figure 1

Measurement of relative levels of glucose, lactate and pyruvate in cells and cell culture medium indicates an increased rate of glycolysis in htt-/- mESCs, but no significant effect of Htt-Q140/7 mutation. Bars depict relative ion abundances measured by LC-MS for the indicated metabolites, measured both in cells (left panels) and in culture media (right panels). Observed fold-changes and p-values are quantified for htt-/- mESC (green bars) and Htt-Q140/7 mutant mESC (red bars), in comparison with wildtype Htt-Q7/7 mESC (yellow bars). Error bars are SEM.