Table 1. Identification of autoantigens reacting against plasma samples from patients with CCA using MMNK1 cell line-derived proteins.
SpotNo. | Protein name | Biologicalprocess | GI number | Protein score | Coverage (%) | MW (kDa) | P-value | Species |
1 | Ribonuclease/angiogenin inhibitor 1 | Angiogenesis | gi|15029922 | 143 | 13 | 50.1 | P<0.05 | Homo sapiens |
2 | Titin | Cardiac muscledevelopment | gi|17066105 | 52 | 1 | 384.3 | P<0.05 | Homo sapiens |
3 | Leucine-rich PPR-motif containing protein | Transcription regulation | gi|801893 | 58 | 6 | 146.3 | ns | Homo sapiens |
4 | MSTP132 | Unknown | gi|33338088 | 47 | 13 | 7.2 | P<0.05 | Homo sapiens |
5 | T-plastin polypeptide | Calcium ion binding | gi|190028 | 49 | 4 | 64.2 | P<0.05 | Homo sapiens |
6 | Enoyl Coenzyme A hydratase 1 | Lipid metabolism | gi|119577225 | 93 | 32 | 14.3 | P<0.05 | Homo sapiens |
7 | PRP38 pre-mRNA processing factor 38 | mRNA processing | gi|33988609 | 123 | 53 | 15.4 | P<0.05 | Homo sapiens |
8 | Alternative protein IPO7 | Unknown | gi|444738577 | 51 | 51 | 12.7 | ns | Homo sapiens |
9 | STIP1 protein | Stress response | gi|73909112 | 53 | 15 | 68.6 | ns | Homo sapiens |
10 | FLJ10996 variant protein | Unknown | gi|68533041 | 58 | 17 | 76.1 | ns | Homo sapiens |
11 | Enolase 1 variant (Alpha-enolase) | Glycolysis, Transcription regulation | gi|62896593 | 482 | 32 | 47.4 | P<0.05 | Homo sapiens |