Table 6. Diagnostic performance (sensitivity, specificity, predictive values) of the possible combination of autoantibodies against HSP70, RNH1 and ENO1 in patients with CCA vs healthy controls.

Combination	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)
HSP70+ENO1	77.42	82.61	85.71	73.08
HSP70+RNH1	87.10	82.61	87.10	82.61
RNH1+ENO1	74.19	78.26	82.14	69.23
HSP70+ENO1+RNH1	70.97	82.61	84.62	67.86

PPV  =  positive predictive value, NPV  =  negative predictive value.