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. 2014 Jul 24;9(7):e103563. doi: 10.1371/journal.pone.0103563

Table 3. Effect of supplementing COC during IVM with different forms of BMP15 (mature BMP15 and pro-mature BMP15), mature GDF9 at 100 ng/ml dose, with and without FSH on blastocyst quality.

Treatments FSH Inner cell mass Trophectoderm Total cell number (TCN) ICM/TCN
Control 24.5±1.9 77.3±5.8 101.8±6.3 0.26±0.02
GDF9 mature 27.4±2.0 73.8±4.6 101.3±5.2 0.28±0.02
BMP15 mature 26.5±1.8 72.1±6.7 98.6±7.9 0.28±0.02
BMP15 pro-mature 29.1±1.8 78.6±6.3 107.7±7.1 0.29±0.02
Control + 30.5±1.6 59.7±3.5 90.2±4.7 0.34±0.01
GDF9 mature + 28.7±1.9 69.7±5.0 98.4±6.0 0.30±0.01
BMP15 mature + 31.8±3.0 68.4±4.4 100.2±6.2 0.31±0.02
BMP15 pro-mature + 34.6±1.8 63.4±2.6 97.9±3.6 0.35±0.01

Data represents the mean ± SEM of 6 replicates. Mean blastocyst cell numbers following differential staining of 22–38 blastocysts.