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. Author manuscript; available in PMC: 2014 Jul 24.
Published in final edited form as: Biomaterials. 2011 Apr 22;32(22):5269–5278. doi: 10.1016/j.biomaterials.2011.03.073

Fig. 4.

Fig. 4

Effects of substituent loading density (%) and molecular weight of the polymer platform. Membranolytic activities were measured using the standard liposome leakage assay. A – C, copolymers P/LLL and P/LOEt with varying amounts of loaded LLL (pH 5.0) or LOEt (pH 5.0 and pH 7.4) at a constant concentration of polymer platform 75 µg/mL. Optimal liposome leakage is seen for ∼ 50% substitution of carboxyl groups. D, membranolyticacitivity of copolymer P/LLL(50%) as a function of varied molecular weight at the copolymer concentration of 0.25 µM. Data represent means ± SEM in triplicate.