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. 2014 Jul 16;14:116. doi: 10.1186/1471-2466-14-116

Table 2.

Sizes of vesicles and internalized particles

Animals Single NP Vesicle
R V/P Cluster
Vesicle
R V/P Cluster
Vesicle
R V/P Cluster
Vesicle
R V/P
1 NP 2-5 NP 2-5 NP 6-10 NP 6-10 NP > 10 NP > 10 NP
OVA-allergic
22.2 ± 1.4
466 ± 64
20.8 ± 2.5
43.4 ± 2.3
459 ± 53
11.1 ± 1.2
78.7 ± 3.3
401 ± 38
5.1 ± 0.4
156 ± 9
393 ± 25
2.7 ± 0.2
 
(n = 16)
 
(n = 26)
 
(n = 22)
 
(n = 38)
 
Sham
21.0 ± 0.7
367 ± 38
17.9 ± 1.9
48.6 ± 3.3
338 ± 41
7.7 ± 1.3
83.5 ± 6.5
414 ± 34
5.2 ± 0.5
182 ± 19
393 ± 32
2.4 ± 0.2
 
(n = 22)
 
(n = 28)
 
(n = 22)
 
(n = 30)
 
Scnn1b-Tg
21.5 ± 0.3
435 ± 30
20.5 ± 1.4
47.9 ± 2.5
393 ± 22
9.4 ± 0.6
74.0 ± 3.3
366 ± 25
5.3 ± 0.4
149 ± 7*
420 ± 19
3.1 ± 0.2
 
(n = 69)
 
(n = 87)
 
(n = 49)
 
(n = 77)
 
WT
22.5 ± 0.4
543 ± 61
24.5 ± 2.8
50.4 ± 3.3
451 ± 43
10.3 ± 1.1
79.1 ± 3.7
404 ± 33
5.3 ± 0.5
188 ± 9
460 ± 20
2.7 ± 0.2
  (n = 46)   (n = 57)   (n = 34)   (n = 74)  

Data are presented as mean values ± SEM. *Significant difference to control group (P = 0.005); n = number of measurements (vesicle and enclosed AuNP). RV/P = ratio of vesicle to particle diameter.