Table 2.
Animals | Single NP |
Vesicle |
R V/P |
Cluster |
Vesicle |
R V/P |
Cluster |
Vesicle |
R V/P |
Cluster |
Vesicle |
R V/P |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 NP | 2-5 NP | 2-5 NP | 6-10 NP | 6-10 NP | > 10 NP | > 10 NP | ||||||
OVA-allergic |
22.2 ± 1.4 |
466 ± 64 |
20.8 ± 2.5 |
43.4 ± 2.3 |
459 ± 53 |
11.1 ± 1.2 |
78.7 ± 3.3 |
401 ± 38 |
5.1 ± 0.4 |
156 ± 9 |
393 ± 25 |
2.7 ± 0.2 |
|
(n = 16) |
|
(n = 26) |
|
(n = 22) |
|
(n = 38) |
|
||||
Sham |
21.0 ± 0.7 |
367 ± 38 |
17.9 ± 1.9 |
48.6 ± 3.3 |
338 ± 41 |
7.7 ± 1.3 |
83.5 ± 6.5 |
414 ± 34 |
5.2 ± 0.5 |
182 ± 19 |
393 ± 32 |
2.4 ± 0.2 |
|
(n = 22) |
|
(n = 28) |
|
(n = 22) |
|
(n = 30) |
|
||||
Scnn1b-Tg |
21.5 ± 0.3 |
435 ± 30 |
20.5 ± 1.4 |
47.9 ± 2.5 |
393 ± 22 |
9.4 ± 0.6 |
74.0 ± 3.3 |
366 ± 25 |
5.3 ± 0.4 |
149 ± 7* |
420 ± 19 |
3.1 ± 0.2 |
|
(n = 69) |
|
(n = 87) |
|
(n = 49) |
|
(n = 77) |
|
||||
WT |
22.5 ± 0.4 |
543 ± 61 |
24.5 ± 2.8 |
50.4 ± 3.3 |
451 ± 43 |
10.3 ± 1.1 |
79.1 ± 3.7 |
404 ± 33 |
5.3 ± 0.5 |
188 ± 9 |
460 ± 20 |
2.7 ± 0.2 |
(n = 46) | (n = 57) | (n = 34) | (n = 74) |
Data are presented as mean values ± SEM. *Significant difference to control group (P = 0.005); n = number of measurements (vesicle and enclosed AuNP). RV/P = ratio of vesicle to particle diameter.