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. 2014 Jul 16;9(7):e102610. doi: 10.1371/journal.pone.0102610

Figure 7. List of potential therapeutic targets for oral cancer.

Figure 7

The right sign ‘✓’ represents significant publication evidence to support association of concerned target gene with a cancer hallmark mentioned in a concerned column, and ‘Inline graphic’ represents absence of such association between gene and cancer hallmark. The ‘Inline graphic’ sign represents significant overexpression of the gene, and ‘Inline graphic’ represents significant under-expression of the gene, observed in oral cancer in study dataset. ‘CausalNet Degree’ is the no. of causally connected genes to the particular target gene. ‘Diff’ is difference in the no. of connections in dependency network, under cancer and control condition for the concerned target gene. ‘MN’ means that annotations for the concerned target gene was inferred from articles related with mouth neoplasm or oral cancer, whereas ‘C’ means that annotations are not specific to oral cancer and were inferred using generic term ‘neoplasms’ or cancer.