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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Hepatology. 2014 Jun 20;60(2):744–753. doi: 10.1002/hep.27043

Figure 3. Genomic loci of lncRNA.

Figure 3

The genomic locations for lncRNAs can be distinct from or can overlap regions that encode can encode for mRNA and proteins. LncRNAs are described in relationship to their location relative to that of nearby protein-coding genes. LncRNA can be transcribed from sense, antisense or both strands relative to the promoter of a protein-coding gene. Intronic lncRNAs initiate inside of an intron of a protein-coding gene in either direction and terminate without overlapping exons. Intergenic lncRNAs, termed lincRNAs, are lncRNAs with separate transcriptional units from protein-coding genes. Overlap may exist between categories, but is not shown. For example, some genes may be partly exonic and partly intronic. Orange arrow indicates a protein coding region. Blue arrows depict lncRNAs.