Table 2.

Modified Intent to Treat Analysis: Estimated Event Rate Ratio and 95% Confidence Interval as a Function of Time for Subjective Vasomotor Symptoms for Women Randomized to Active Stellate Ganglion Blockade (SGB) or the sham-control.

	Treatment Group		Treatment Group × Time
	SGB	Sham-control	Treatment Group × Time

Primary Outcomes	RR (95%CI)	RR (95%CI)	RRR (95%CI)
Baseline to Week 1
Total	0.76 (0.61–0.96)^*	0.75 (0.61–0.93)^**	1.01 (0.74–1.39)
Moderate-to-very severe	0.73 (0.54–1.00)^‡	0.74 (0.56–0.98)^*	0.99 (0.65–1.50)
Baseline to Months 1–3
Total	0.68 (0.57–0.83)^***	0.68 (0.56–0.80)^***	1.03 (0.80–1.34)
Moderate-to-very severe	0.62 (0.48–0.80)^***	0.69 (0.55–0.87)^**	0.90 (0.64–1.27)
Baseline to Months 4–6
Total	0.66 (0.54–0.81)^***	0.82 (0.69–0.98)^*	0.81 (0.62–1.03)^T
Moderate-to-very severe	0.48 (0.36–0.63)^***	0.96 (0.77–1.20)	0.50 (0.35–0.71)^***

Note.

^***

p<0.001;

^**

p<0.01;

p<0.05;

^‡

p=0.05;

p=0.10; SGB=Stellate Ganglion Blockade; CI = Confidence Interval; RR = Event Rate Ratio; RRR=Ratio of Event Rate Ratios. Results are reflective of a mixed effects Poisson regression (random intercept only).