Table I.
Clinicopathological data for 48 AML patients taken in a study
Number of patients | 48 |
Gender(M/F) | 23/25 |
Age of study, range (median) | 25–73 (52year) |
Peripheral blood values | |
WBC (K/μl) range (median) | 0.3–70.6 (4.8) |
Bone marrow blasts, range (median) | 5–94% (29%) |
WHO | |
AML –t (9:11)(p22;q23) | 2 |
AML-inv(16)(p13.1;q22) | 1 |
AML, NOS | 31 |
AML-t | 3 |
AML-MDS | 9 |
Other | 2 |
FAB | |
M0 | 2 |
M1 | 7 |
M2 | 13 |
M4 | 4 |
M5 | 5 |
M6 | 3 |
RAEB-T | 7 |
Other/NA | 6 |
Mix | 1 |
Cytogenetic findings | |
Recurrent genetic abnormalities | 3 |
Diploid | 18 |
1–2 Abnormalities | 11 |
Complex (>3 abnormalities) | 16 |
Mutation Status (Positive/Tested) | |
NRAS | 4/40 (10%) |
KRAS | 2/40 (5%) |
KIT | 1/24 (4 %) |
FLT3-D835 | 3/46 (7%) |
FLT3-ITD | 5/46 (11%) |
NPM1 | 1/4 (25%) |