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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: J Exp Zool B Mol Dev Evol. 2014 Jan 24;322(6):438–463. doi: 10.1002/jez.b.22558

Figure 2. Immunoglobulin heavy chain genome organization in Latimeria chalumnae.

Figure 2

Genomic scaffolds containing the two extended IgH loci were downloaded and annotated. Analyses of these L. chalumnae scaffolds confirm that they also possess two IgW heavy chain loci, which correspond unequivocally to L. menadoensis IgW1 and IgW2. Orthologous IgW1 and IgW2 loci between the two species are highly similar (>99% identical across alignable regions). A locus encoding a heavy chain recognizable as Cµ was not identified either from bioinformatics searches or via direct hybridization and PCR screening strategies.