Skip to main content
. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Clin J Pain. 2014 Dec;30(12):1033–1043. doi: 10.1097/AJP.0000000000000077

Table 2.

Mediation of treatment effects on parent-reported child GI symptom severity and pain at 3, 6 and 12 months by changes from baseline to 1 week post-treatment in parental threat, parental solicitousness, and child catastrophizing

a c’ b a*b Effect size of
the indirect
effect (a*b)
Parent-reported
outcome		 Estimate
(SE)		 90 CI 95 CI Estimate
(SE)		 90 CI 95 CI Estimate
(SE)		 90 CI 95 CI Estimate
(SE)		 90 CI 95 CI Hedges’ g
Severity at 3 months
 Parent threat −0.18
(0.03)		 −0.23,
−0.13		 −0.24,
−0.12		 0.01
(0.06)		 −0.09,
0.11		 −0.11,
0.13		 0.32
(0.09)		 0.17,
0.47		 0.14,
0.50		 −0.06
(0.02)		 −0.09,
−0.03		 −0.09,
−0.02		 −0.43
 Parent
 solicitousness		 −0.21
(0.03)		 −0.26,
−0.16		 −0.27,
−0.15		 0.01
(0.06)		 −0.09,
0.11		 −0.11,
0.13		 0.09
(0.10)		 −0.08,
0.26		 −0.11,
0.29		 −0.02
(0.02)		 −0.05,
0.02		 −0.06,
0.02		 −0.13
 Child CAT −0.12
(0.05)		 −0.20,
−0.04		 −0.22,
−0.02		 0.01
(0.06)		 −0.09,
0.11		 −0.11,
0.13		 0.08
(0.07)		 −0.04,
0.20		 −0.06,
0.22		 −0.01
(0.01)		 −0.02,
0.01		 −0.03,
0.01		 −0.15
Severity at 6 months
 Parent threat −0.18
(0.03)		 −0.23,
−0.13		 −0.24,
−0.12		 −0.01
(0.05)		 −0.09,
0.07		 −0.11,
0.09		 0.30
(0.07)		 0.18,
0.42		 0.16,
0.44		 −0.05
(0.02)		 −0.08,
−0.03		 −0.08,
−0.02		 −0.49
 Parent
 solicitousness		 −0.21
(0.03)		 −0.26,
−0.16		 −0.27,
−0.15		 −0.01
(0.05)		 −0.09,
0.07		 −0.11,
0.09		 0.002
(0.09)		 −0.15,
0.15		 −0.17,
0.18		 −0.0004
(0.02)		 −0.03,
0.03		 −0.04,
0.04		 −0.003
 Child CAT −0.12
(0.05)		 −0.20,
−0.04		 −0.22,
−0.02		 −0.01
(0.05)		 −0.09,
0.07		 −0.11,
0.09		 −0.01
(0.06)		 −0.11,
0.09		 −0.13,
0.11		 0.001
(0.01)		 −0.01,
0.01		 −0.01,
0.02		 0.02
Severity at 12 months
 Parent threat −0.17
(0.03)		 −0.22,
−0.12		 −0.23,
−0.11		 −0.001
(0.06)		 −0.10,
0.10		 −0.12,
0.12		 0.33
(0.09)		 0.18,
0.48		 0.15,
0.51		 −0.06
(0.02)		 −0.09,
−0.03		 −0.09,
−0.02		 −0.44
 Parent
 solicitousness		 −0.21
(0.03)		 −0.26,
−0.16		 −0.27,
−0.15		 −0.001
(0.06)		 −0.10,
0.10		 −0.12,
0.12		 0.14
(0.11)		 −0.04,
0.32		 −0.08,
0.36		 −0.03
(0.02)		 −0.07,
0.01		 −0.08,
0.02		 −0.18
 Child CAT −0.12
(0.05)		 −0.20,
−0.04		 −0.22,
−0.02		 −0.001
(0.06)		 −0.10,
0.10		 −0.12,
0.12		 0.03
(0.07)		 −0.09,
0.15		 −0.11,
0.17		 −0.004
(0.01)		 −0.02,
0.01		 −0.02,
0.01		 −0.06
Pain at 3 months
 Parent threat −0.18
(0.03)		 −0.23,
−0.13		 −0.24,
−0.12		 −0.02
(0.19)		 −0.33,
0.29		 −0.39,
0.35		 1.26
(0.27)		 0.82,
1.71		 0.73,
1.79		 −0.23
(0.06)		 −0.33,
−0.13		 −0.35,
−0.11		 −0.52
 Parent
 solicitousness		 −0.21
(0.03)		 −0.26,
−0.16		 −0.27,
−0.15		 −0.02
(0.19)		 −0.33,
0.29		 −0.39,
0.35		 0.34
(0.32)		 −0.19,
0.87		 −0.29,
0.97		 −0.07
(0.07)		 −0.18,
0.04		 −0.20,
0.06		 −0.15
 Child CAT −0.12
(0.05)		 −0.20,
−0.04		 −0.22,
−0.02		 −0.02
(0.19)		 −0.33,
0.29		 −0.39,
0.35		 0.37
(0.21)		 0.02,
0.72		 −0.04,
0.78		 −0.04
(0.03)		 −0.10,
0.007		 −0.11,
0.02		 −0.20
Pain at 6 months
 Parent threat −0.18
(0.03)		 −0.23,
−0.13		 −0.24,
−0.12		 −0.15
(0.20)		 −0.48,
0.18		 −0.54,
0.24		 0.88
(0.29)		 0.40,
1.36		 0.31,
1.45		 −0.16
(0.06)		 −0.25,
−0.06		 −0.27,
−0.04		 −0.38
 Parent
 solicitousness		 −0.21
(0.03)		 −0.26,
−0.16		 −0.27,
−0.15		 −0.15
(0.20)		 −0.48,
0.18		 −0.54,
0.24		 −0.27
(0.34)		 −0.83,
0.29		 −0.94,
0.40		 0.06
(0.07)		 −0.06,
0.18		 −0.08,
0.20		 0.11
 Child CAT −0.12
(0.05)		 −0.20,
−0.04		 −0.22,
−0.02		 −0.15
(0.20)		 −0.48,
0.18		 −0.54,
0.24		 0.03
(0.22)		 −0.33,
0.39		 −0.40,
0.46		 −0.004
(0.03)		 −0.05,
0.04		 −0.06,
0.05		 −0.02
Pain at 12 months
 Parent threat −0.18
(0.03)		 −0.23,
−0.13		 −0.24,
−0.12		 0.24
(0.18)		 −0.06,
0.54		 −0.11,
0.59		 0.87
(0.25)		 0.46,
1.28		 0.38,
1.36		 −0.16
(0.05)		 −0.24,
−0.07		 −0.26,
−0.06		 −0.43
 Parent
 solicitousness		 −0.20
(0.03)		 −0.25,
−0.15		 −0.26,
−0.14		 0.24 (0.18) −0.06,
0.54		 −0.11,
0.59		 0.32
(0.30)		 −0.18,
0.82		 −0.27,
0.91		 −0.06
(0.06)		 −0.16,
0.04		 −0.18,
0.06		 −0.15
 Child CAT −0.12
(0.05)		 −0.20,
−0.04		 −0.22,
−0.02		 0.24 (0.18) −0.06,
0.54		 −0.11,
0.59		 0.25
(0.20)		 −0.08,
0.58		 −0.14,
0.64		 −0.03
(0.03)		 −0.07,
0.01		 −0.08,
0.02		 −0.16

Note.

a

= change in the mediator from baseline to post−treatment due to SLCBT treatment compared to ES;

b

= direct effect of change in the mediator from baseline to post−treatment on change in the outcome;

c’

= direct effect of treatment on the outcome variable;

a*b

=indirect (mediated) effect of treatment on the outcome. To facilitate interpretation of the table, Hedges’ g for the a*b effect was bolded if the .90 confidence intervals (CI) excluded zero, suggesting that mediation is present. Hedges’ g values can be interpreted approximately as follows: .80 large, .50 medium and .20 small.

HHS Vulnerability Disclosure