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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Clin J Pain. 2014 Dec;30(12):1033–1043. doi: 10.1097/AJP.0000000000000077

Table 3.

Mediation of treatment effects on child-reported GI symptom severity and pain at 3, 6 and 12 months by changes from baseline to 1 week post-treatment in parental threat, parental solicitousness, and child catastrophizing

a c’ b a*b Effect size
of the
indirect
effect
(a*b)
Child-reported outcome Estimate
(SE)		 90 CI 95 CI Estimate
(SE)		 90 CI 95 CI Estimate
(SE)		 90 CI 95
CI		 Estimate
(SE)		 90 CI 95
CI		 Hedges’ g
Severity at 3 months
 Parent threat −0.17
(0.03)		 −0.22,
−0.12		 −0.23,
−0.11		 0.02
(0.05)		 −0.06,
0.10		 −0.08,
0.12		 0.06
(0.07)		 −0.06,
0.18		 −0.08,
0.20		 −0.01
(0.01)		 −0.03,
0.01		 −0.03,
0.01		 −0.12
 Parent solicitousness −0.21
(0.03)		 −0.26,
−0.16		 −0.27,
−0.15		 0.02
(0.05)		 −0.06,
0.10		 −0.08,
0.12		 −0.01
(0.08)		 −0.14,
0.12		 −0.17,
0.15		 0.002
(0.02)		 −0.03,
0.03		 −0.03,
0.03		 0.02
 Child CAT −0.12
(0.05)		 −0.20,
−0.04		 −0.22,
−0.02		 0.02
(0.05)		 −0.06,
0.10		 −0.08,
0.12		 0.14
(0.05)		 0.06,
0.22		 0.04,
0.24		 −0.02
(0.01)		 −0.03,
−0.002		 −0.03,
−0.001		 −0.26
Severity at 6 months
 Parent threat −0.18
(0.03)		 −0.23,
−0.13		 −0.24,
−0.12		 −0.003
(0.05)		 −0.09,
0.08		 −0.10,
0.10		 0.13
(0.07)		 0.02,
0.25		 −0.01,
0.27		 −0.02
(0.01)		 −0.05,
−0.002		 −0.05,
0.002		 −0.25
 Parent solicitousness −0.21
(0.03)		 −0.26,
−0.16		 −0.27,
−0.15		 −0.003
(0.05)		 −0.09,
0.08		 −0.10,
0.10		 −0.08
(0.08)		 −0.21,
0.05		 −0.24,
0.08		 0.02
(0.02)		 −0.01,
0.04		 −0.02,
0.05		 0.14
 Child CAT −0.12
(0.05)		 −0.20,
−0.04		 −0.22,
−0.02		 −0.003
(0.05)		 −0.09,
0.08		 −0.10,
0.10		 0.18
(0.05)		 0.10,
0.26		 0.08,
0.28		 −0.02
(0.01)		 −0.04,
−0.004		 −0.04,
0.0004		 −0.28
Severity at 12 months
 Parent threat −0.18
(0.03)		 −0.23,
−0.13		 −0.24,
−0.12		 −0.11
(0.06)		 −0.21,
−0.01		 −0.23,
0.01		 0.05
(0.09)		 −0.10,
0.20		 −0.13,
0.23		 −0.01
(0.02)		 −0.04,
0.02		 −0.04,
0.02		 −0.08
 Parent solicitousness −0.21
(0.03)		 −0.26,
−0.16		 −0.27,
−0.15		 −0.11
(0.06)		 −0.21,
−0.01		 −0.23,
0.01		 −0.08
(0.10)		 −0.25,
0.09		 −0.28,
0.12		 0.02
(0.02)		 −0.02,
0.05		 −0.02,
0.06		 0.11
 Child CAT −0.12
(0.05)		 −0.20,
−0.04		 −0.22,
−0.02		 −0.11
(0.06)		 −0.21,
−0.01		 −0.23,
0.01		 0.12
(0.07)		 0.004,
0.24		 −0.02,
0.26		 −0.01
(0.01)		 −0.03,
0.003		 −0.03,
0.006		 −0.20
Pain at 3 months
 Parent threat −0.18
(0.03)		 −0.23,
−0.13		 −0.24,
−0.12		 0.03
(0.13)		 −0.18,
0.24		 −0.22,
0.28		 0.59
(0.19)		 0.28,
0.90		 0.22,
0.96		 −0.11
(0.04)		 −0.17,
−0.04		 −0.18,
−0.03		 −0.39
 Parent solicitousness −0.21
(0.03)		 −0.26,
−0.16		 −0.27,
−0.15		 0.03
(0.13)		 −0.18,
0.24		 −0.22,
0.28		 −0.16
(0.23)		 −0.54,
0.22		 −0.61,
0.29		 0.03
(0.05)		 −0.05,
0.11		 −0.06,
0.13		 0.10
 Child CAT −0.12
(0.05)		 −0.20,
−0.04		 −0.22,
−0.02		 0.03
(0.13)		 −0.18,
0.24		 −0.22,
0.28		 0.24
(0.15)		 −0.01,
0.49		 −0.05,
0.53		 −0.03
(0.02)		 −0.06,
0.007		 −0.07,
0.01		 −0.19
Pain at 6 months
 Parent threat −0.18
(0.03)		 −0.23,
−0.13		 −0.24,
−0.12		 0.06
(0.12)		 −0.14,
0.26		 −0.18,
0.30		 0.37
(0.17)		 0.09,
0.65		 0.04,
0.70		 −0.07
(0.03)		 −0.12,
−0.01		 −0.13,
−0.003		 −0.29
 Parent solicitousness −0.21
(0.03)		 −0.26,
−0.16		 −0.27,
−0.15		 0.06
(0.12)		 −0.14,
0.26		 −0.18,
0.30		 −0.37
(0.20)		 −0.70,
−0.04		 −0.76,
0.02		 0.08
(0.04)		 0.006,
0.15		 −0.01,
0.16		 0.25
 Child CAT −0.12
(0.05)		 −0.20,
−0.04		 −0.22,
−0.02		 0.06
(0.12)		 −0.14,
0.26		 −0.18,
0.30		 0.26
(0.13)		 0.05,
0.47		 0.005,
0.52		 −0.03
(0.02)		 −0.06,
0.002		 −0.07,
0.009		 −0.22
Pain at 12 months
 Parent threat −0.17
(0.03)		 −0.22,
−0.12		 −0.23,
−0.11		 0.09
(0.13)		 −0.12,
0.30		 −0.16,
0.34		 0.28
(0.19)		 −0.03,
0.59		 −0.09,
0.65		 −0.05
(0.03)		 −0.10,
0.007		 −0.11,
0.02		 −0.20
 Parent solicitousness −0.21
(0.03)		 −0.26,
−0.16		 −0.27,
−0.15		 0.09
(0.13)		 −0.12,
0.30		 −0.16,
0.34		 −0.10
(0.23)		 −0.48,
0.28		 −0.55,
0.35		 0.02
(0.05)		 −0.06,
0.10		 −0.07,
0.12		 0.06
 Child CAT −0.12
(0.05)		 −0.20,
−0.04		 −0.22,
−0.02		 0.09
(0.13)		 −0.12,
0.30		 −0.16,
0.34		 0.16
(0.15)		 −0.09,
0.41		 −0.13,
0.45		 −0.02
(0.02)		 −0.05,
0.01		 −0.06,
0.02		 −0.14

Note.

a

= change in the mediator from baseline to post−treatment due to SLCBT treatment compared to ES;

b

= direct effect of change in the mediator from baseline to post−treatment on change in the outcome;

c’

= direct effect of treatment on the outcome variable;

a*b

=indirect (mediated) effect of treatment on the outcome. To facilitate interpretation of the table, Hedges’ g for the a*b effect was bolded if the .90 confidence intervals (CI) excluded zero, suggesting that mediation is present. Hedges’ g values can be interpreted approximately as follows: .80 large, .50 medium and .20 small.

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