Figure 4.
Addition of glutathione eliminates the sulfenic acid metabolite. A. Concentration-dependent yield of the AGN 3 sulfenic acid in the presence of glutathione. Metabolite was reduced even when GSH was added 15 min after incubation began. The percent metabolite on the y axis is compared to the yield in the absence of glutathione. B. Mass spectrum and proposed mass fragmentation pathwy of the glutathione adduct of AGN 3.