TABLE 3.
Complete blood count analysis of mice from Sec24c+/− × Sec24d+GT intercrosses
Tail bleeds were carried out at 8–12 weeks of age. Data from males and females were pooled after confirming no significant difference between males and females of the same genotypes. The following abbreviations are used: HGB, hemoglobin; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, MCH concentration; RDW, red cell distribution width; PLT, platelet count; MPV, mean platelet volume.
| Parameter | Genotype |
|||
|---|---|---|---|---|
| Sec24c+/+ | Sec24c+/− | Sec24d+/GT | Sec24c+/− Sec24d+/GT | |
| WBC (× 103 cells/μl) | 7.4 ± 0.9 | 8.2 ± 1.3 | 9.9 ± 1.4 | 9.0 ± 1.1 |
| RBC (× 106 cells/μl) | 8.7 ± 0.8 | 9.5 ± 0.3 | 9.7 ± 0.2 | 9.9 ± 0.3 |
| HGB (g/dl) | 12.2 ± 1.0 | 12.2 ± 0.5 | 13.3 ± 0.2 | 13.0 ± 0.5 |
| HCT (%) | 45.2 ± 2.6 | 45.7 ± 1.5 | 48.5 ± 0.7 | 48.4 ± 1.3 |
| MCV (fl) | 48.8 ± 0.6 | 48.1 ± 0.5 | 49.8 ± 0.4 | 49.1 ± 0.4 |
| MCH (pg) | 13.1 ± 0.3 | 12.6 ± 0.2 | 13.6 ± 0.1 | 13.1 ± 0.1 |
| MCHC (g/dl) | 26.9 ± 0.7 | 26.3 ± 0.5 | 27.2 ± 0.4 | 26.8 ± 0.4 |
| RDW (%) | 13.5 ± 0.3 | 13.5 ± 0.2 | 13.9 ± 0.5 | 14.0 ± 0.6 |
| PLT (× 103 cells/μl) | 976.0 ± 171.7 | 1221.7 ± 53.3 | 1186.7 ± 80.9 | 1076.3 ± 73.0 |
| MPV (fl) | 5.3 ± 0.6 | 5.0 ± 0.2 | 4.8 ± 0.2 | 5.1 ± 0.2 |