TABLE 2.

Receptor binding-induced changes for 2 interspin distances in arrestin-3

Distance changes for two double-labeled arrestin-3 mutants. Arr3-free, inactive state of arrestin-3; Arr3 + PR*, arrestin-3 upon binding to light-activated and phosphorylated rhodopsin. ΔDistance, distance change between the two residues upon PR* binding.

	Arrestin-3 doubles	PRONOX, Arr3-free	DEER, Arr3-free	DEER, Arr3 + PR*	ΔDistance
		Å	Å	Å	Å
C-tail	13/392	15	22	31, 43, 54	4, 16, 27
Finger loop	68/168	7	22, 43	24, 43	2, 0