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. 2014 Jun 5;289(30):21003–21015. doi: 10.1074/jbc.M114.553073

FIGURE 8.

FIGURE 8.

FbsC is a virulence factor of GBS. Comparison of lethality and bacterial burden in mice infected with wild-type NEM316 (WT) or its fbsC deletion (ΔfbsC) mutant. A and B, survival of CD1 mice following intraperitoneal infection with WT or with ΔfbsC strains using, as challenge, 4 × 108 (A) and 2 × 108 (B) cfu/mouse. *, p < 0.05 by log-rank Kaplan-Meyer analysis. C, blood and kidney colony counts at 24 h after intraperitoneal challenge with 1 × 108 cfu of WT or ΔfbsC strains. *, p < 0.05 by analysis of variance and Student's Neuman Keuls test. D, blood and brain colony counts in mice infected intravenously with 4 × 108 cfu of WT or ΔfbsC strains. *, p < 0.05 by analysis of variance and Student's Neuman Keuls test.