Fig. 1.

Structures showing prominent vacuolation at four levels of coronal sections. Diagrams are from The Mouse Brain Library DBA2J atlas (www.mbl.org). Regions with consistent vacuolation are shown by white circles on one side of the brain; all lesions are bilaterally symmetric. Regions involved include: 1 – molecular layer of piriform area, 2 – layer 2 of taenia tecta (a); 1 – anterior cingulate cortex, 2 – layer 5 of primary motor area, 3 – layer 5 of primary somatosensory area, 4 – molecular layer of piriform area (b); 1 – retrosplenial cortex, 2 – hippocampus CA3, 3 – layer 5 of primary motor, somatosensory, visual cortex, 4 – piriform area (c); 1 – retrosplenial cortex, 2 – layer 5 of visual cortex, 3 – parts of hippocampus including part of CA3, 4 – piriform area (d)