Table 5.
Other structural imaging.
| Clinical features |
Imaging |
||||||
|---|---|---|---|---|---|---|---|
| ET and controls, age (SD) or *median (range) | ET | Cri | Results ET vs HC | Data analysis | |||
| Oliveira et al. (2012), 1.5T | 33 ET *79(74–87) | 507 HC *78(75–82) | UE | Ls | ↑ | Total WMH Cerebellar WMH, temporal WMH |
T2-FLAIR MRI WMH in ROI: cerebellum, frontal lobe, basal ganglia, occipital, parietal, temporal lobes Pcor < 0.05 |
| Novellino et al. (2013), 3T | 24 ET 64.3(10.0) | 25 HC 64.2(9.3) | UE, head, dys |
D | ↑ | Bilateral globus pallidus, substantia nigra, right dentate nucleus (Punc < 0.001) Bilateral pallidum (FWE P < 0.05) |
Whole brain R2* (1/T2*) maps Punc < 0.001 and FWE P < 0.05 |
Cor, multiple comparison corrected; Cri, criteria; D, Deuschl et al. (1998); dys, dystonic features; ET, essential tremor; FWE, family wise error; head, head tremor; HC, healthy controls; Ls, Louis et al. (2001); ROI, region of interest; SD, standard deviation; UE, upper extremity; Punc, multiple comparison uncorrected; vs, versus; WMH, white matter hyperintensities.