Table 2.

Differences in estimated onset of morphometric change in relationship to symptom onset for the amygdala, entorhinal cortex and hippocampus. The p-value, corrected for multiple comparisons, is obtained for each structure via permutation tests, as described in the Methods section (the lowest detectable p-value is 10⁻⁴). The reported onset time for each structure is estimated via bootstrap (the standard deviation between parentheses measuring its accuracy).

Side		Amygdala volume	Amygdala segment	Hippocampus volume	Hippocampus segment	ERC volume	ERC segment
Left	p-Value	0.003	0.006	0.017	0.13	0.0001	0.0001
	Avg. Δ (std.)	2.8 (2.3)	2.5 (1.4)	3.1 (1.9)	2.6 (1.0)	7.5 (2.5)	8.6 (1.5)
Right	p-Value	0.006	0.0015	0.27	0.024	0.0007	0.004
	Avg. Δ (std.)	2.5 (3.3)	2.7 (1.9)	4.0 (3.8)	3.6 (1.4)	9.9 (3.0)	8.5 (2.8)