Table 1.
National Institutes of Health randomized study: Long-term intraperitoneal 5-fluorouracil can prevent the occurrence of peritoneal metastases n (%)
Sites of treatment failure for IV or IP 5-FU |
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No. of patients | No. of recurrences | Peritoneal surface | Liver | |
IP 5-FU | 36 | 13 (36) | 2/10 | 3/11 |
IV 5-FU | 30 | 11 (37) | 10/11 | 4/11 |
Statistical analysis P2 | 0.003 | 1.000 |
From ref. [11] with permission. 5-FU: 5-fluorouracil.