Table 1.

Analysis of Crystal Hits from NESG Protein Samples with Various Monodispersity (2001–2007)

Year	Monodispese	Predominantly monodisperse	Mostly polydisperse	Polydisperse	Indeterminate	Aggregated
2001	1/2 (50.0%)
2002	24/82 (29.3%)	0/4 (0.0%)
2003	14/52 (26.9%)	1/3 (33.3%)	1/1 (100.0%)			0/1 (0.0%)
2004	42/112 (37.5%)	6/19 (31.6%)	0/11 (0.0%)	0/110 (0.0%)		0/35 (0.0%)
2005	37/148 (25.0%)	2/31 (6.5%)	1/9 (11.1%)	0/24 (0.0%)	0/20 (0.0%)	0/27 (0.0%)
2006	37/223 (16.6%)	14/41 (34.1%)	2/32 (6.3%)	2/30 (6.7%)	1/46 (2.2%)	1/25 (4.0%)
2007	47/277 (17.0%)	7/57 (12.3%)	0/26 (0.0%)	0/19 (0.0%)	1/69 (1.4%)	1/70 (1.4%)
Total	202/896 (22.5%)	30/155 (19.4%)	4/79 (5.1%)	2/183 (1.1%)	2/135 (1.5%)	2/158 (1.3%)

Proteins with crystal hits/Proteins provided for crystallization screening (% crystal hits)

Monodisperse: >90% monodispersity

Predominantly monodisperse: >80% but <90% monodispersity

Mostly polydisperse: >50% but <80% monodispersity and <3 peaks

Polydisperse: <50% monodispersity with > 3 peaks

Indeterminate: protein not in void volume (V_o), but obscured by ring-down from V_o

Aggregated: protein in V_o.