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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: J Immunol. 2014 Jun 25;193(3):1314–1323. doi: 10.4049/jimmunol.1400089

FIGURE 3.

FIGURE 3

VD treatment reduced pathogenic T cell sequestration in the brain. (A) VD treatment of PbA-infected mice reduced the number of CD4+ and CD8+ T cells in the brains (n=5). Values are means plus SEMs (error bars). (B,C) VD treatment significantly reduced the expression of the chemokines CXCL9 and CXCL10 in the brains of PbA-infected mice. The mRNA levels for the two chemokines were normalized to the β-actin mRNA level, and fold changes were calculated against control uninfected mice. * indicates significant difference between mRNA levels in infected mice on day 5 and their corresponding baseline levels on day 0 (P<0.05). # indicates significant difference (P<0.05) between the PbA and PbA+VD groups on day 5 p.i.