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Table 3.

OR and 95% CI for mtDNA copy number and B-NHL overall and subtype of CLL according to follow-up time

Logistic regression
Q1 (6.7-23.6) Q2 (23.7-29.4) Q3 (29.5-36.2) Q4 (36.3-294.7) P trend
B-NHL*
 ≤4.6 y follow-up
  n (case/control) 48/50 43/56 38/47 77/53
  Adjusted OR (95% CI) Ref. 0.81 (0.40-1.62) 0.87 (0.42-1.80) 1.34 (0.71-2.55) .18
 >4.6 y follow-up
  n 64/57 34/49 47/57 67/49
  Adjusted OR (95% CI) Ref. 0.52 (0.28-0.96) 0.75 (0.41-1.36) 1.16 (0.62-2.16) .53
B-NHL without MM*
 ≤4.6 y follow-up
  n 32/38 28/37 26/33 58/36
  Adjusted OR (95% CI) Ref. 1.00 (0.44-2.27) 1.25 (0.50-3.11) 2.09 (0.97-4.51) .02
 >4.6 y follow-up
  n 50/46 27/35 35/48 53/36
  Adjusted OR (95% CI) Ref. 0.63 (0.31-1.27) 0.60 (0.30-1.18) 1.31 (0.65-2.62) .59
CLL
 ≤4.6 y follow-up
  n 6/117 8/117 8/118 26/117
  Adjusted OR (95% CI) Ref. 1.24 (0.41-3.68) 1.46 (0.49-4.35) 3.70 (1.44-9.52) .001
 >4.6 y follow-up
  n 8/117 12/117 13/118 21/117
  Adjusted OR (95% CI) Ref. 1.40 (0.56-3.52) 1.43 (0.58-3.54) 2.39 (0.99-5.78) .05

Quartiles (Q) number (minimum-maximum); P trend is the P value (2 sided) calculated by including the quartile number as a continuous variable.

Ref., reference.

*

Conditional logistic regression model adjusted for smoking status and educational level.

Unconditional logistic regression model adjusted for age at recruitment, sex, country, smoking status, educational level, and plate number.