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Summary of statistical significance of candidate disease-associated genes in prostate cancer progression#
| Database | Known reported genes | Genes in the HPC-PPIN | Candidate disease-associated genes | HD, RS (P-values) |
|---|---|---|---|---|
| Cancer Gene | 488 | 129 | 23 | 6 × 10-4, |
| Census | <3 × 10-4 | |||
| GAD | 309 (prostate cancer only | 155 | 22 | 7 × 10-3, 7 × 10-3 |
| AnimalTFDB (Transcription factors) | 1,457 | 121 | 18 | 9 × 10-3, 7 × 10-3 |
#Abbreviations: HD: Hypergeometric Distribution, RS: Random Sampling
