Table 1.
Signal-to-noise ratio, weight and proportion of different types of seed matches in different regions.
2t8A1 | 2t8 | 2t7A1 | 2t7 | 1t8GU | ||
---|---|---|---|---|---|---|
Number of matches (miRWalk) | 1,235 | 3,105 | 2,657 | 7,296 | 3,734 | Promoters |
171 | 628 | 463 | 1,594 | 730 | 5'UTRs | |
1,153 | 3,116 | 2,729 | 6,494 | 3,343 | CDSs | |
2,366 | 4,103 | 3,204 | 6,920 | 3,797 | 3'UTRs | |
Number of matches (Average of 50 times random shuffle) | 911 | 2,639 | 2,422 | 7,014 | 3,068 | Promoters |
141 | 489 | 391 | 1,415 | 547 | 5'UTRs | |
904 | 2,331 | 2,331 | 5,997 | 2,655 | CDSs | |
1,069 | 2,593 | 2,513 | 6,060 | 3,175 | 3'UTRs | |
Signal-to-noise ratio | 1.355 | 1.177 | 1.097 | 1.040 | 1.217 | Promoters |
1.213 | 1.284 | 1.184 | 1.126 | 1.333 | 5'UTRs | |
1.275 | 1.337 | 1.171 | 1.083 | 1.259 | CDSs | |
2.214 | 1.583 | 1.275 | 1.142 | 1.196 | 3'UTRs | |
Weight | 0.293 | 0.146 | 0.080 | 0.033 | 0.179 | Promoters |
0.176 | 0.234 | 0.151 | 0.104 | 0.275 | 5'UTRs | |
0.227 | 0.277 | 0.141 | 0.068 | 0.214 | CDSs | |
1.000 | 0.480 | 0.227 | 0.117 | 0.161 | 3'UTRs | |
Proportion (miRWalk) | 7% | 17% | 15% | 40% | 21% | Promoters |
5% | 18% | 13% | 44% | 20% | 5'UTRs | |
7% | 19% | 16% | 39% | 20% | CDSs | |
12% | 20% | 16% | 34% | 19% | 3'UTRs | |
Proportion (Average of 50 times shuffle) | 6% | 16% | 15% | 44% | 19% | Promoters |
5% | 16% | 13% | 47% | 18% | 5'UTRs | |
6% | 16% | 16% | 42% | 19% | CDSs | |
7% | 17% | 16% | 39% | 21% | 3'UTRs |
The number of matches in miRWalk dataset is the real number of each seed match type in each target region. The number of matches from random shuffles is the average number of each type of seed match over 50 randomly shuffled mRNA sequences. The signal-to-noise ratio is the ratio of these two numbers. The weight is then calculated via the equation (1). The proportion is the percentage of a specific seed match type in each target region.