Table 2.
Groups | Dose (mg/kg) | No. of writhing | % inhibition |
---|---|---|---|
Group I | Vehicle | 30.5(±1.136) | |
Group II | 10 | 7.75(±1.306)* | 74.59 |
Group III | 300 | 8.75 (±1.489)* | 71.31 |
Group IV | 500 | 5.25(±1.581)* | 82.79 |
Values are mean±SEM, (n = 4);
p<0.05 as compared with vehicle control (one way ANOVA followed by Dunnet’s test). Group I animals received vehicle (1% Tween 80 in water), Group II (Standard) received diclofenac sodium 10 mg/kg body weight, Group III and IV were treated with 300 and 500 mg/kg body weight (p.o.) of the methanolic extract of Lawsonia inermis barks, respectively.