Table 5.
Group | Dose |
Number of Movements
|
||||
---|---|---|---|---|---|---|
0 min | 30 min | 60 min | 90 min | 120 min | ||
Group-I | 10 ml/kg, | 12 ± 1.716 | 16.75± 1.717 | 17.75±1.307 | 17.75± 1.307 | 19.25±1.489 |
Group-II | 1 mg/kg, | 15.75 ± 1.307 | 5.0± 1.107* | 3.5± 1.136* | 2.75± 0.978* | 2.00 ± 0.904 |
Group-III | 300 mg/kg | 4.5 ± 1.443* | 3.0±1.495* | 2.25±1.622* | 1.25± 1.376* | - |
Group-IV | 500 mg/kg | 3.00 ± 1.351* | 2.0± 1.0* | 1.5± 1.136* | 0.5±0.760* | - |
Values are mean±SEM, (n = 4),
p<0.05, Dunnet’s test as compared with vehicle control. Group I animals received vehicle (1% Tween 80 in water), Group II received diazepam 1 mg/kg body weight, Group III and Group IV were treated with 300 and 500 mg/kg body weight (p.o.) of the methanolic extract of Lawsonia inermis barks, respectively.