Table 6.
Group | Dose |
Number of Movements
|
||||
---|---|---|---|---|---|---|
0 min | 30 min | 60 min | 90 min | 120 min | ||
Group-I | 10 ml/kg | 119 ± 1.469 | 115 ± 1.77 | 108.75±2.234 | 98.25±2.305 | 106.25± 1.942 |
Group-II | 1 mg/kg | 107.25± 2.510 | 72 ± 2.450* | 49.5± 1.908* | 21.25±1.608* | 11.5±1.641 |
Group-III | 300 mg/kg, | 237.5 ± 5.00* | 108.5± 4.533 | 69.75±5.019* | 30±4.272* | - |
Group-IV | 500 mg/kg, | 160.5± 8.612 | 94.75± 5.659 | 88.75±5.475 | 49±6.026* | - |
Values are mean±SEM, (n = 4),
p<0.05, Dunnet’s test as compared with vehicle control. Group I animals received vehicle (1% Tween 80 in water), Group II received diazepam 1 mg/kg body weight, Group III and Group IV were treated with 300 and 500 mg/kg body weight (p.o.) of the methanolic extract of Lawsonia inermis barks, respectively.