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. 2014 Jul-Aug;4(4):287–296.

Table 6.

Effect of methanolic extract of the bark of Lawsonia inermis on Open Field test in mice

Group Dose Number of Movements
0 min 30 min 60 min 90 min 120 min
Group-I 10 ml/kg 119 ± 1.469 115 ± 1.77 108.75±2.234 98.25±2.305 106.25± 1.942
Group-II 1 mg/kg 107.25± 2.510 72 ± 2.450* 49.5± 1.908* 21.25±1.608* 11.5±1.641
Group-III 300 mg/kg, 237.5 ± 5.00* 108.5± 4.533 69.75±5.019* 30±4.272* -
Group-IV 500 mg/kg, 160.5± 8.612 94.75± 5.659 88.75±5.475 49±6.026* -

Values are mean±SEM, (n = 4),

*

p<0.05, Dunnet’s test as compared with vehicle control. Group I animals received vehicle (1% Tween 80 in water), Group II received diazepam 1 mg/kg body weight, Group III and Group IV were treated with 300 and 500 mg/kg body weight (p.o.) of the methanolic extract of Lawsonia inermis barks, respectively.