Table 1.
Increase of IFNs and ISG Expression in Stem Cell-Derived Hepatocytes after Treatment with IL-29 or HCV
| Gene Symbol | RefSeq | Fold Increase |
Gene Description | |
|---|---|---|---|---|
| IL-29 Treatment | HCV Treatment | |||
| IFIT1 | NM_001548 | 2,488.73 | 4.64 | IFN-induced protein with tetratricopeptide repeats 1 |
| IFI27 | NM_005532 | 927.55 | 5.91 | alpha-inducible protein 27 |
| IFI44 | NM_006417 | 389.86 | 6.64 | IFN-induced protein 44 |
| IFI44L | NM_006820 | 216.25 | 2.54 | IFN-induced protein 44-like |
| IFIT2 | NM_001547 | 152.75 | 3.41 | IFN-induced protein with tetratricopeptide repeats 2 |
| IFI6 | NM_002038 | 111.52 | 5.12 | IFN, alpha-inducible protein 6 |
| CXCL10 | NM_001565 | 110.63 | 4.32 | chemokine (C-X-C motif) ligand 10 |
| OAS1 | NM_002534 | 88.16 | 5.73 | 2′-5′-oligoadenylate synthetase 1, 40/46 kDa |
| ISG15 | NM_005101 | 52.36 | 4.35 | ISG15 ubiquitin-like modifier |
| IFIH1 | NM_022168 | 51.89 | 4.19 | IFN induced with helicase C domain 1 |
| IFITM1 | NM_003641 | 20.27 | 6.29 | IFN-induced transmembrane protein 1 (9–27) |
| IRF7 | NM_001572 | 18.56 | 12.51 | IFN regulatory factor 7 |
| IFNA8 | NM_002170 | 16.90 | 6.49 | IFN, alpha 8 |
| IFI35 | NM_005533 | 11.27 | 5.65 | IFN-induced protein 35 |
| MX1 | NM_002462 | 11.26 | 4.66 | myxovirus (influenza virus) resistance 1, IFN-inducible protein p78 (mouse) |
| IL-29 | NM_172140 | 10.99 | 7.10 | IL-29 (IFN, lambda 1) |
See also Table S3.