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. 2012 Aug;3(4):157–164. doi: 10.1177/2042098612446473

Table 3.

Absolute and relative risk of treatment-emergent inpatient and outpatient claims associated with diagnoses of pancreatic and thyroid neoplasm among exenatide and metformin or glyburide initiators, Normative Health Information database, 1 June 2005−31 December 2009.

Cases (N) Patients (N) Absolute risk (%) Relative risk 95% CI
Cases identified from inpatient or outpatient claims
All thyroid neoplasms
Exenatide 46 32,807 0.1 1.2 0.7–1.8
Metformin/glyburide 40 32,828 0.1 1 reference
Benign thyroid neoplasms
Exenatide 11 32,877 0 0.7 0.3–1.7
Metformin/glyburide 15 32,879 0 1 reference
Thyroid malignancies
Exenatide 37 32,822 0.1 1.4 0.8–2.4
Metformin/glyburide 26 32,842 0.1 1 reference
Pancreatic malignancy
Exenatide 21 32,889 0.1 0.8 0.5–1.6
Metformin/glyburide 25 32,878 0.1 1 reference
Cases identified from inpatient claims only
All thyroid neoplasms
Exenatide 7 32,894 0.0 0.7 0.2–2.0
Metformin/glyburide 10 32,894 0.0 1.0 reference
Benign thyroid neoplasms
Exenatide 0 32,894 0.0 0.0 0.0–4.1
Metformin/glyburide 2 32,894 0.0 1.0 reference
Thyroid malignancies
Exenatide 7 32,894 0.0 0.9 0.3–2.6
Metformin/glyburide 8 32,894 0.0 1.0 reference
Pancreatic malignancy
Exenatide 12 32,894 0.0 0.5 0.2–1.1
Metformin/glyburide 23 32,894 0.1 1.0 reference

CI, confidence interval.